Waterloo 42, Cambridge 39
Freshman Brittany Limoseth scored 12 of her 17 points in the second half to carry the host Pirates over the Blue Jays.
The win was Waterloo's first victory over Cambridge since 2005-2006.
Limoseth and junior Ashley Battenberg made 4-of-6 free throws at the end to seal the win.
Waterloo made six 3-pointers.
Sophomore Joriann Clary scored 13 points for Cambridge.